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Extended Release niacin and pantethine in one tablet. Endur-thine® helps support healthy lipoprotein metabolism, promoting normal cholesterol and triglyceride levels already within normal limits.*

Caution: Temporary flushing, itching, or warming of the skin may occur. Do not use without the advice of your physician if you consume more than modest amounts of alcohol, have poorly controlled diabetes, liver disease, gout, active peptic ulcer disease, or unstable angina.

Endur-thine® is a dietary supplement containing a unique combination of 500 mg extended release niacin (Endur-acin®) and 200 mg extended release pantethine per tablet. Both Endur-acin® and pantethine have been clinically proven to support a healthy cholesterol profile already within normal limits*. The “sustained release” feature of each tablet means slow, steady absorption of both ingredients over time, helping to prevent the commonly experienced “niacin-flush” that can occur with high doses of niacin.

The beneficial effects of niacin (B3) have been documented since the discovery in 1955. Pantethine is the metabolic precursor of the vitamin pantothenic acid (B5) and has also shown in studies on both diabetic and non-diabetic populations. Pantethine, not pantothenic acid, has been shown to affect healthy cholesterol.

Endur-acin® has been clinically tested at Harvard and the University of Minnesota. In a study including 201 male and female subjects, it was very well tolerated and clinically safe (complete study results available at www.enduranceresearch.com. Nuisance side effects of immediate-release niacin, especially flushing of the skin, were notably reduced or eliminated by the sustained release formulation of Endur-acin®.

Pantethine has been clinically studied as Pantesin®  (http://www.pantesin.com/).  Pantethine is very well tolerated, and like niacin, favorably healthy affects on a lipoprotein profile, but by different mechanisms than niacin. This makes it a good combination.

When combined with a diet low in saturated fat and dietary cholesterol, Endur-thine® provides an effective regimen for promoting healthy cholesterol and triglyceride levels already within normal limits*.

Directions: As a dietary supplement for adults, take one tablet daily with food. Do not exceed one tablet daily without consulting a physician. These tablets are specially manufactured to release the active ingredients continuously over a 5-7 hour period. 

  *These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.