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Glucosamine and Chondroitin have been studied in over 100 clinical trials and have been shown to be safe and effective in reducing the normal wear and tear on joints from day to day activity.

The recent LEGS study again confirms that the combination helped maintain normal joint space compared to placebo, supporting healthy joint function and mobility*.

More than 50 million men and women in the United States suffer from debilitating joint conditions that severely affect quality of life.  Glucosamine and chondroitin have emerged as both a safe and effective solution in maintaining healthy joint function and mobility*.

Glucosamine is an amino sugar precursor to components of cartilage called glycosaminoglycans, which are necessary for cartilage production.  Chondroitin is the most abundant glycosaminoglycan in cartilage and inhibits production of enzymes that can degrade cartilage.  Numerous studies of glucosamine and chondroitin have been conducted demonstrating that both of these natural substances are well absorbed, and are safe and well tolerated.  Most studies have focused on glucosamine.  A study published inThe Lancet compared radiographic evidence in 212 patients given either glucosamine or placebo over a three-year period.  Results of the study showed that patients supplementing with glucosamine maintained a greater amount of articular cartilage than placebo*.

Virtually all studies have utilized three daily doses, since glucosamine remains in the blood for a short time.  Endur-flex® is a sustained release formulation which prolongs the release of the active ingredients and enables a twice daily regimen.  Endur-flex® also uses glucosamine hydrochloride rather than glucosamine sulfate.  The hydrochloride form provides almost twice the bioactive ingredient as the sulfate form by weight. Therefore,Endur-flex® actually provides more bioactive glucosamine in two tablets than most other products supply in three tablets.

Directions: Take three tablets daily. For best results take one tablet with each meal.


  *These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.