Heart Health
Supplements that help us maintain the health of our entire cardiovascular system – heart, blood vessels, and normal functions.

Heart Health
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View All ProductsSupplements that help us maintain the health of our entire cardiovascular system – heart, blood vessels, and normal functions.
ENDUR-ACIN® 500mg Extended Release Niacin (Nicotinic Acid)

Extended Release
Extended Release
From $22.99
Promotes cardiovascular health and the normal production of cellular energy in all heart and vascular tissues. Extended-release delivery helps reduce flushing side effect.
At-a-Glance
- Promotes heart health & cholesterol balance*
- Extended-release delivery helps eliminate flushing & digestive upset*
- Provides a gradual, measured release of nicotinic acid over 6 to 8 hours
- Backed by a portfolio of clinical research
- Drug-free and available without a prescription
- Formulated to complement doctor-recommended therapeutic lifestyle changes*
Product Description
ENDUR-ACIN® Extended Release Niacin is ideal for adults interested in advanced nutritional support for heart health and cholesterol balance.*
ENDUR-ACIN® provides nicotinic acid – the only form of niacin with targeted benefits for heart health and lipid metabolism – in a proprietary vegetable-based wax matrix. The unique wax-matrix delivery system not only ensures a gradual, measured release of nicotinic acid over a 6 to 8 hour period, but also helps eliminate digestive upset and skin flushing that can occur with immediate-release forms.*
ENDUR-ACIN® is backed by clinical research and may help maintain healthy cholesterol levels within the normal range.* “Flush-free” forms of niacin may reduce flushing, but these forms have not been clinically shown to benefit heart health.
ENDUR-ACIN® is available in three strengths – 250 mg, 500 mg, and 750 mg – for easy compliance with doctor recommendations.
Features
- Easy-to-swallow tablets
- No salt, sugar, starch, artificial colors or flavorings, or preservatives
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
- Free of other allergens (corn, yeast)
Frequently Asked Questions
What can you expect?
ENDUR-ACIN® Extended Release Niacin is a unique dietary supplement for men and women to support heart health and cholesterol balance. In the body, each tablet dissolves slowly to release nicotinic acid at the preferred rate to support cholesterol balance. It is specifically formulated to complement doctor-recommended lifestyle changes for overall cardiovascular health.*
How does it work?
In the body, each tablet dissolves slowly over 6 to 8 hours to release nicotinic acid at the preferred rate to support cholesterol balance. ENDUR-ACIN® is available in three strengths – 250 mg, 500 mg and 750 mg – for easy compliance with your doctor’s recommendations..
How do you take it?
As a dietary supplement for adults, take one tablet daily with food. Do not exceed one tablet daily without consulting a physician.
Are there any precautions?
- Consult your healthcare professional prior to use if you have or suspect a medical condition, or are taking any medications. Not recommended for women who are pregnant or nursing.
- Do not use without the advice of your physician if you consume more than modest amounts of alcohol, have poorly controlled diabetes, liver disease, gout, active peptic ulcer disease, or unstable angina.
- Some sensitive people may experience temporary flushing, itching or warming of the skin.
- As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
ENDUR-ACIN® is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
Phytosterols 450mg Plant Sterols

Immediate Release
$39.99 Sold Out
Plant sterols help block cholesterol absorption in the small intestine to support overall cardiovascular health and cholesterol balance.
At-a-Glance
- May reduce heart disease risk**
- Immediate-release delivery maximizes cholesterol-blocking action*
- Supports prostate & urinary tract health in men*
Product Description
Phytosterols Immediate Release (IR) is ideal for adults interested in heart health, and men interested in prostate and urinary tract health.*
Phytosterols IR features immediate-release delivery, a key advantage for heart health. When taken as directed, Phytosterols IR delivers plant sterols that enter the intestine before cholesterol in food, where they are primed to help block the absorption of cholesterol into the body.*
Phytosterols IR also has targeted benefits for men’s health to support urinary tract health, urinary flow, and prostate health.*
**Foods and supplements containing at least 400 mg per serving of plant sterols, eaten twice a day with meals for a daily total intake of at least 800 mg, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. A serving of Phytosterols IR supplies 450 mg of phytosterols.
Features
- Easy-to-swallow tablets
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat)
(sourced from sunflower and other vegetable oils) - Convenient one-tablet serving, taken before meals
Frequently Asked Questions
What can you expect?
Phytosterols IR provides nutritional support for both men and women for overall heart health. For men, Phytosterols IR also provides targeted support for prostate and urinary tract health.*
How does it work?
Phytosterols IR may help reduce the risk of heart disease by lowering elevated total and LDL (“bad”) blood cholesterol, which are key risk factors for heart disease. For men, Phytosterols IR provides a clinically effective amount of phytosterols shown to promote optimal urinary tract health, urinary flow, and prostate health.*
How do you take it?
Take one (1) tablet at the beginning of a meal, twice daily, or as directed by your healthcare professional.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are pregnant or nursing. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
Phytosterols IR is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
L-Arginine 350mg Sustained Release

Sustained Release
Sustained Release
From $36.99
An amino acid that may help maintain healthy blood vessel function, optimal blood flow, endothelial health, and blood pressure in the normal range.
At-a-Glance
- Helps maintain healthy blood pressure in the normal range*
- Supports cardiovascular health and blood vessel function*
- Promotes healthy nitric oxide production*
- Features sustained-release delivery for optimal absorption
Product Description
L-Arginine Sustained Release (SR) is an advanced dietary supplement designed for adults interested in overall cardiovascular health, including maintaining healthy blood pressure in the normal range.*
L-Arginine SR features the amino acid L-Arginine in a unique vegetable-based wax matrix that releases L-Arginine gradually. An optimal blood level of L-Arginine is critical for vascular health. Your endothelium – the layer of cells that line your blood vessels – relies on this amino acid for a healthy production of nitric oxide. In turn, nitric oxide plays a key role in vascular health, including promoting blood vessel relaxation and optimal blood flow.*
L-Arginine SR and its ability to support blood vessel health is ideally suited for athletes, active adults and others interested in maintaining healthy blood vessel function. Adults interested in overall health can benefit from L-Arginine SR as well. L-Arginine – one of the body’s most metabolically versatile amino acids – also plays a role in immune health, detoxification, protein synthesis, hormone regulation, male fertility, and more.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Features
- No salt, starch, preservatives, artificial color or flavorings
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
- Convenient, easy-to-swallow tablets
Frequently Asked Questions
What can you expect?
L-Arginine SR is a unique dietary supplement specially formulated for adults to support vascular health, including healthy blood vessel function.*
How does it work?
Each tablet dissolves slowly for a steady release of L-Arginine over 4 to 6 hours. This promotes optimal absorption and tissue retention without an excessive amount of Arginine typically found in regular immediate-release forms.*
How do you take it?
As a dietary supplement for adults, take three (3) tablets twice daily, preferably with meals, or as directed by your healthcare practitioner. It is normal for this product to have a distinctive botanical aroma.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are nursing or pregnant. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
L-Arginine SR is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
ENDUR-VM® Multi-Vitamin & Mineral without Iron

Sustained Release
From $19.99
Supports cardiovascular health with 22 essential vitamins and minerals (plus iron if needed) including antioxidants, energizing B vitamins, D3, and trace minerals.
At-a-Glance
- Balanced, high-potency formula
- 22 essential vitamins and minerals
- Without iron for men and postmenopausal women
- Sustained-release delivery for high bioavailability
- Available with iron for women of childbearing years.
Product Description
ENDUR-VM® Multi-Vitamin & Mineral Sustained Release (SR) (Without Iron) is an innovative iron-free daily multivitamin formulated for heart health, with selenium, folate, biotin, and B vitamins. It is especially beneficial for mature adults to help counteract an age-related decline in nutrient absorption.*
ENDUR-VM® SR (Without Iron) is a high-potency formula with 22 essential vitamins and minerals, including protective antioxidants, energizing B vitamins, vitamin D3, and trace minerals.
ENDUR-VM® SR (Without Iron) features a proprietary vegetable-based wax matrix that gradually releases nutrients over a 4-6 hour period for high absorption and tissue retention.*
Also available with iron to support the nutritional needs of people prone to low iron levels.
Features
- Easy-to-swallow tablets
- No salt, sugar, starch, artificial colors or flavorings, or preservatives
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
Frequently Asked Questions
What can you expect?
ENDUR-VM® SR (Without Iron) is a convenient, once-daily solution for men and postmenopausal women to help fill nutrient gaps that can occur between what your typical diet provides and what your body needs for optimal health.*
How does it work?
By using a proprietary wax matrix delivery technology, each tablet dissolves slowly, resulting in a continuous release of nutrients over 4 to 6 hours. This promotes high nutrient absorption and optimal tissue retention, especially for water-soluble B vitamins and vitamin C.
How do you take it?
As a dietary supplement for adults, take one (1) tablet daily with a full glass of water, preferably with a meal. It is normal for this product to have a distinctive botanical aroma.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are nursing or pregnant. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
ENDUR-VM® SR (Without Iron) is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
Pantethine 300mg SR from Pantesin®

Sustained Release
From $38.99
An active form of vitamin B5, it promotes heart health and healthy cholesterol, lipid metabolism, and liver health*.
At-a-Glance
- Promotes heart health*
- Supports healthy cholesterol & lipid metabolism*
- Energizes cellular metabolism*
- Helps maintain healthy liver detoxification*
- Sustained-release delivery for high bioavailability
Product Description
Pantethine from Pantesin® Sustained Release (SR) is ideal for adults who want targeted nutritional support for healthy cholesterol, lipid metabolism, and liver health.*
Pantethine SR combines Pantesin®, a highly absorbable form of the B vitamin pantethine, with sustained-release tablet delivery for optimal absorption. Pantesin® is backed by clinical research and over 30 years of safe and effective use in Japan for heart health.*
Pantethine SR works by providing a key building block for Coenzyme A, your body’s most active metabolic enzyme. CoA is required to activate a wide variety of biochemical reactions critical for whole body health. It plays a central role in converting food into cellular energy. CoA helps convert choline into acetylcholine, an important biochemical messenger for nerve cell communication. It activates enzymes required to produce hormones, hemoglobin and other bioactive compounds. CoA even activates enzymes in the liver that help remove toxins from the body. It also works deep within cells, activating enzymes that play a key role in maintaining healthy cholesterol balance & lipid metabolism.*
PANTESIN® is a registered trademark of Daiichi Fine Chemical Co., Ltd.
Features
- Easy-to-swallow tablets
- No salt, sugar, preservatives, artificial colors or flavorings
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
Frequently Asked Questions
What can you expect?
Pantethine SR is a unique dietary supplement for men and women that supports overall heart health, cholesterol balance, and liver function.*
How does it work?
In the body, each tablet dissolves slowly to release pantethine at a steady, continuous rate to promote optimal absorption.
How do you take it?
As a dietary supplement for adults, take one (1) tablet, twice daily, with morning and evening meals, or as directed by your healthcare practitioner. It is normal for this product to have a distinctive botanical aroma.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are pregnant or nursing. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
Pantethine SR is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
ENDUR-ACIN® 250mg Extended Release Niacin (Nicotinic Acid)

Extended Release
Extended Release
From $16.99
Promotes cardiovascular health and the normal production of cellular energy in all heart and vascular tissues. Extended-release delivery helps reduce flushing side effect.
At-a-Glance
- Promotes heart health & cholesterol balance*
- Extended-release delivery helps eliminate flushing & digestive upset*
- Provides a gradual, measured release of nicotinic acid over 6 to 8 hours
- Backed by a portfolio of clinical research
- Drug-free and available without a prescription
- Formulated to complement doctor-recommended therapeutic lifestyle changes*
Product Description
ENDUR-ACIN® 250mg Extended Release Niacin is ideal for adults interested in advanced nutritional support for heart health and cholesterol balance.*
ENDUR-ACIN® provides nicotinic acid – the only form of niacin with targeted benefits for heart health and lipid metabolism – in a proprietary vegetable-based wax matrix. The unique wax-matrix delivery system not only ensures a gradual, measured release of nicotinic acid over a 6 to 8-hour period, but also helps eliminate digestive upset and skin flushing that can occur with immediate-release forms.*
ENDUR-ACIN® is backed by clinical research and may help maintain healthy cholesterol levels within the normal range.* “Flush-free” forms of niacin may reduce flushing, but these forms have not been clinically shown to benefit heart health.
ENDUR-ACIN® is available in three strengths –- 250 mg, 500 mg and 750 mg -– for easy compliance with doctor recommendations.
Features
- Easy-to-swallow tablets
- No salt, sugar, starch, artificial colors or flavorings, or preservatives
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
- Free of other allergens (corn, yeast)
Frequently Asked Questions
What can you expect?
ENDUR-ACIN® is a unique dietary supplement for men and women to support heart health and cholesterol balance. It is specifically formulated to complement doctor-recommended lifestyle changes for overall cardiovascular health.*
How does it work?
Each tablet dissolves slowly over 6 to 8 hours to release nicotinic acid at the preferred rate to support cholesterol balance. ENDUR-ACIN® is available in three strengths – 250 mg, 500 mg and 750 mg – for easy compliance with your doctor’s recommendations.
How do you take it?
As a dietary supplement for adults, take one (1) tablet daily with food. Do not exceed one tablet daily without consulting a physician.
Are there any precautions?
- Consult your healthcare professional prior to use if you have or suspect a medical condition or are taking any medications. Not recommended for women who are pregnant or nursing.
- Do not use without the advice of your physician if you consume more than modest amounts of alcohol, have poorly controlled diabetes, liver disease, gout, active peptic ulcer disease, or unstable angina.
- Some sensitive people may experience temporary flushing, itching or warming of the skin.
- As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
ENDUR-ACIN® is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
ENDUR-B® Complex SR

Sustained Release
From $24.99
With eight essential B vitamins, including vitamin B6, folic acid, and vitamin B12, it supports heart health by helping maintain homocysteine levels in the normal range.
At-a-Glance
- Balanced, high-potency formula with all 8 essential B vitamins
- Supports healthy energy levels*
- Promotes heart health*
- Helps maintain homocysteine already in the normal range*
- Sustained-release delivery for high bioavailability
Product Description
ENDUR-B® Complex Sustained Release (SR) is ideal for healthy adults – especially dieters, athletes, mature adults, and people interested in heart health – to ensure an optimal intake of B vitamins or fuel higher metabolic demands.*
ENDUR-B® Complex SR features high-potency B vitamins in a proprietary vegetable-based wax matrix specifically designed to release B vitamins gradually over a 5 to 7 hour period for optimal absorption and tissue retention.*
Your body relies on B vitamins for a wide range of functions. In particular, Vitamin B6, folic acid, and vitamin B12 provide heart health benefits by helping to maintain a healthy homocysteine level in the normal range. Yet unlike fat-soluble vitamins, water-soluble B vitamins are not stored in body tissues and require daily replenishment.*
Features
- Easy-to-swallow tablets
- NO salt, sugar, starch, artificial colors or flavorings, or preservatives
- Gluten-free
- Vegan/Vegetarian
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
- Free of other allergens (corn, yeast)
- Convenient once daily serving
Frequently Asked Questions
What can you expect?
ENDUR-B® Complex SR provides a convenient, once-daily solution to not only support heart health, but also nourish your whole body and energize your healthy lifestyle.*
How does it work?
Each tablet dissolves slowly over 5 to 7 hours for a slow and steady release of B vitamins to promote optimal absorption and tissue retention.
How do you take it?
As a dietary supplement for adults, take one (1) tablet daily with a full glass of water, preferably with a meal.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are nursing or pregnant. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
ENDUR-B® Complex SR is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
Co-Enzyme Q10 Crystal-Free

Immediate Release
$46.99
Featuring CoQsol-CF®, a crystal-free form of CoQ10 (ubiquinone), vitamin E, and mixed tocopherols, it promotes heart health and energy production in the heart.
At-a-Glance
- Promotes heart & blood vessel health*
- Supports the body’s antioxidant defenses*
- Helps maintain healthy cell function*
- Helps replenish blood levels of CoQ10, which may be depleted by statin drugs*
Product Description
Co-Enzyme Q10 is ideal for adults who want nutritional support for heart health as well as whole body health. It is especially helpful for people who take statin drugs.*
Co-Enzyme Q10 features CoQsol-CF® a highly soluble, crystal-free form of CoQ10 (ubiquinone) along with high-potency vitamin E and mixed tocopherols.
Co-Enzyme Q10 is specially formulated to overcome common barriers to CoQ10 absorption that can occur with regular powdered forms. With its superior CoQ10 absorption which is backed by clinical research, each easy-to-swallow soft gel helps you maintain high blood levels of this important nutrient.
CoQ10 exerts dual benefits for heart and whole body health. First, it works inside the mitochondria – the energy factory of cells – to produce energy; especially in the heart, muscles and other tissues with high metabolic demands. Second, CoQ10 functions as a powerful antioxidant, neutralizing free radicals that can damage cells. Vitamin E and mixed tocopherols complete the formula for additional antioxidant protection.*
CoQsol-CF® is a registered trademark of Soft Gel Technologies Inc.
Features
- Easy-to-swallow softgels
- No salt, starch, preservatives, artificial colors or flavorings
- Gluten-free
- Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
Frequently Asked Questions
What can you expect?
Co-Enzyme Q10 works to fortify your body’s antioxidant defenses, fuel cellular energy production, and help replenish blood levels of CoQ10, which may be depleted by statin drugs.*
How does it work?
Each soft gel provides 100 mg of water-soluble, crystal-free CoQ10, which is readily absorbed and taken into the bloodstream where it can be delivered to cells, tissues, and organs for antioxidant protection and for cellular energy production.*
How do you take it?
As a dietary supplement for adults, take one (1) to two (2) soft gels twice daily, preferably with meals, or as directed by your healthcare practitioner.
Are there any precautions?
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are pregnant or nursing. As with all dietary supplements, keep out of reach of children.
What product quality control tests are performed?
Co-Enzyme Q10 is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.
MegaNatural®-BP 150mg Grape Seed Extract

Sustained Release
On Sale from $18.99
Regular price
$24.99
BP features a unique grape seed extract from California grapes provides beneficial polyphenols – powerful antioxidants – that help us maintain healthy blood pressure and healthy blood vessel function.
At-a-Glance
- Promotes blood vessel health*
- Supports whole body antioxidant health*
- Sustained-release for high bioavailability
- Sourced from 100% California grapes
Product Description
MegaNatural®-BP Grape Seed Extract Sustained Release (SR) is ideal for adults interested in targeted nutritional support for blood vessel health as well as whole body antioxidant health.*
MegaNatural®-BP SR features a unique, standardized form of grape seed extract which is sustainably sourced from 100% California grapes, water-extracted without chemicals or solvents, and backed by clinical research. The extract is precisely layered into a proprietary vegetable-based wax matrix. The result is a unique product that allows the bioactive grape polyphenols to gradually release in the intestine where they are readily available for absorption.*
Grape seed polyphenols are naturally occurring plant antioxidants that help neutralize free radicals that can cause cellular damage. Free radicals are unstable molecules produced during normal metabolism, but also as a result of intense exercise or exposure to sun, pollution, smoking or other environmental toxins.*
MegaNatur