A joint health supplement containing glucosamine and chondroitin sulfate, which are vital components for maintaining, rebuilding, and repairing cartilage and supporting joint lubrication.*

Active adults seeking to preserve mobility, athletes demanding peak joint performance, seniors maintaining flexibility, and anyone seeking support for joint comfort.*

As a dietary supplement for adults, take three (3) tablets daily. For best results take one (1) tablet with each meal. It is normal for this product to have a distinctive botanical aroma.

Glucosamine and chondroitin are commonly used to support joint health and promote mobility and comfort during physical activity. These ingredients may also help maintain overall joint flexibility and hydration, contributing to a sense of well-being. Additionally, glucosamine has been studied for its potential roles in supporting skin health and general recovery after exercise.

Glucosamine is an amino monosaccharide that supports cartilage repair and regeneration. Chondroitin sulfate helps support joint lubrication and promote cartilage health (1). Together, they work to maintain overall joint function. One meta-analysis of 30 randomized controlled trials reveals glucosamine predominantly promotes joint flexibility, while chondroitin is more likely to support joint comfort and mobility (2). In addition, some researchers report glucosamine promotes an athlete’s ability to maintain joint health, an action attributed to supporting healthy cartilage metabolism (3). Others report glucosamine supports the health of aging skin, an action largely attributed to its role in collagen and hyaluronic acid production.(4).

Vegetable wax (rice bran and/or carnauba), stearic acid (vegetable), magnesium stearate (vegetable), and silica.

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are pregnant or nursing. As with all dietary supplements, keep out of reach of children.

ENDUR-FLEX® is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.

1. Jerosch J. Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially omega-3 fatty acids. Int J Rheumatol. 2011;2011:969012. doi:10.1155/2011/969012.
2. Zhu X, Sang L, Wu D, Rong J, Jiang L. Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2018;13(1):170. doi:10.1186/s13018-018-0871-5
3. Nagaoka I, Tsuruta A, Yoshimura M. Chondroprotective action of glucosamine, a chitosan monomer, on the joint health of athletes. Int J Biol Macromol. 2019;132:795-800. doi:10.1016/j.ijbiomac.2019.03.234
4. Gueniche A, Castiel-Higounenc I. Efficacy of Glucosamine Sulphate in Skin Ageing: Results from an ex vivo Anti-Ageing Model and a Clinical Trial. Skin Pharmacol Physiol. 2017;30(1):36-41. doi:10.1159/000450832