As soon as October rolls around, so does the unofficial season of sugar.

From Halloween candy to pumpkin spice everything, holiday cocktails to December desserts, the last three months of the year are a sugar minefield — especially for adults over 45. And while occasional treats are part of life, the added load on your metabolic system during this time can be real.

That’s why many health-conscious consumers turn to supplements for metabolic support — especially berberine, a compound long used to promote healthy blood sugar and lipid metabolism. But there’s a problem, and it’s a big one.

Berberine is very poorly absorbed.

Makes sense when you know the reasons why. First, berberine is only slightly soluble in water, making it difficult to absorb. Plus, a carrier protein in your intestine actively works to push much of the berberine back into the gut rather than allowing it to enter the blood.

Second, some people lack the friendly gut bacteria that can help convert berberine into dihydroberberine, which is more efficiently absorbed—about 5x better than berberine.

It’s a biochemical bottleneck that requires large amounts of berberine for enough to be absorbed, amounts that can cause digestive upset.

For anyone trying to support metabolic health consistently, that’s a serious problem.

Fortunately, there’s a smarter solution: dihydroberberine — a next-generation form of berberine designed for better absorption, optimal bioactivity, and steady, sustained support.

The Problem with Standard Berberine

Berberine has earned its place in the metabolic support toolkit. It’s been studied for decades and is widely used to help support:

• Glucose balance

• Insulin sensitivity

• Lipid metabolism

• Cellular energy production

All good stuff but for that pesky absorption issue.

Common issues with standard berberine:

• Low bioavailability: Very little makes it into the bloodstream

• GI distress: Some users experience bloating or discomfort

• Short activity window: Requires frequent dosing for sustained support

The result? People take berberine thinking they’re supporting their metabolism — but get limited impact, or none at all.

Dihydroberberine: The Smarter Form

Instead of relying on the unpredictability of berberine, you can supplement with dihydroberberine, its highly bioavailable chemical cousin, body ready for high absorption. In other words, you eliminate the biggest barrier: absorption.

What makes dihydroberberine better?

• Up to 5x more bioavailable than standard berberine

• Easily crosses the intestinal cells for optimal absorption

• Lower dosing promotes digestive comfort

Dihydroberberine helps maintain healthy blood sugar in the normal range, supports normal insulin sensitivity, helps maintain energy production at the cellular level, and promotes more stable metabolic function — all with improved tolerability.

This is especially important during high-sugar seasons, when your body’s ability to manage glucose, fats, and energy demand is put to the test.

Here's the breakdown:

The SmartMatrix™ Advantage

Even though dihydroberberine is a lot easier for your body to absorb than regular berberine, using a reliable delivery system can help make it work even better for you. That’s where our SmartMatrix™ tablet technology shines.

Using this proprietary technology, Endur™ tablets avoid sugary coatings, artificial ingredients and unnecessary binders typical of common tablets. Instead, tablets are made by encasing dihydroberberine in a vegetable wax matrix for precision release over several hours, much like the body digests food. We call them Secure Release™ tablets. You can call them metabolic support at its best.

What makes Secure Release™ tablets better?

• Encased, not coated: Nutrients are embedded in a vegetable wax matrix for precision release

• Targeted GI delivery: Designed to release where absorption actually happens

• Sustained nutrient availability: No spike, no crash — just stable support

• Laboratory validated: Proven to release up to 99% of active ingredients

By pairing dihydroberberine with SmartMatrix™ technology, Endur™ Dihydroberberine SR helps ensure that your metabolic support supplement actually does what it’s supposed to — steadily and predictably, with the digestive comfort you deserve.*

Holiday Metabolic Support Matters More

During the holidays, blood sugar levels often swing more than usual — not just from sweets, but from big meals, alcohol, travel disruptions, and changes in sleep or activity levels.

This puts extra pressure on your:

• Insulin response

• Cellular energy production

• Fat metabolism

• Nervous system and focus

Supporting metabolic efficiency through this season isn’t just about short-term comfort — it’s about maintaining long-term resilience.

Dihydroberberine offers a stimulant-free way to help your body:

• Maintain stable energy

• Support glucose balance and insulin function

• Promote balanced fat metabolism

• Stay metabolically resilient through a demanding season

Why It Pairs Well with Niacinamide

Our Metabolic Health Bundle includes both dihydroberberine (Dihydroberberine SR) and niacinamide (Endur-Amide®) — and for good reason.

Where dihydroberberine supports healthy glucose metabolism and mitochondrial energy, niacinamide supports healthy:*

• Lipid metabolism

• NAD+ production (critical for cellular repair and longevity)

• Inflammatory balance

• Cardiovascular and neurological function

Together, they provide multi-pathway metabolic support — from glucose balance to fat metabolism to cellular health.*

This is a smart, science-backed combo for adults who want to keep their edge — especially through the most metabolically demanding months of the year.

Choose Quality for Optimal Benefits

The ENDUR™ Metabolic Health Bundle features formulas with research-backed ingredients, in amounts that can have meaningful benefits. With Secure Release™ tablets, you can be confident you’re supporting what matters most for optimal metabolic health:

• Glucose balance and lipid metabolism

• Energy production

• Insulin sensitivity

• Metabolic resilience

All without relying on caffeine, stimulants, or synthetic additives.

Conclusion: Smarter Support Starts Here

Not all supplements are created equal — and with berberine, the difference between standard and smart could mean everything.

As we head into the sugar-filled, stress-loaded, schedule-busting season of the year, give your metabolism the kind of support it actually recognizes and uses.

Dihydroberberine + niacinamide, delivered in Secure Release™ Tablets — it’s not just smarter science. It’s the support your body deserves.

SmartMatrix™ is a trademark of Innovite, Inc.

 *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.